News & Publications

NEWS & PUBLICATIONS

Learn more about Prous Institute and our progress in drug discovery, technology, industry partnerships, collaborations and scientific articles.


Prous Institute Symmetry has been used by the U.S. Department of Health and Human Services’ National Toxicology Program (NTP) as part of a battery of in silico analyses of the potential toxicity of chemicals spilt in January 2014 in the Elk River, West Virginia, U.S.A.   A chemical mixture used for cleaning coal was accidently released into the river, resulting in contaminati...


Symmetry's Global Mechanism of Action (GMoA) model provides decision support in the multi-target approach to deliberately combine in a single molecule scaffolds related to different therapeutic targets. This case study is performed with molecules reported in a recent paper describing the first compound exhibiting gamma-Secretase modulation, PPARgamma agonism and 5-LOX inhibition for the potential ...


Prous Insitute is pleased to announce the launch of our new website showcasing the features and benefits of Symmetry, the world’s first integrated predictive platform for drug discovery and safety evaluation.  To visit the website please click here.   


Prous Institute has been invited to speak at the R&D Head Club Meeting taking place in Tokyo, Feb. 6, 2015 at the Kitasato University School of Pharmacy Convention Hall. The meeting, organized by Professor Masahiro Takeuchi from Kitasato University’s, School of Pharmaceutical Sciences, will bring together an audience of clinical research mangers from leading Japanese and multinational ph...


Symmetry's Global Mechanism of Action (GMoA) model helps anticipate potential off-target safety liabilities of new structures early in drug discovery. This case study is performed with molecules reported in a recent paper describing the optimization of compounds for the potential treatment of Alzheimer ’s disease, minimizing cardiovascular liabilities (hERG channel blockade). To recei...

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