News & Publications

NEWS & PUBLICATIONS

Learn more about Prous Institute and our progress in drug discovery, technology, industry partnerships, collaborations and scientific articles.


30 April 2015.  Ryoka Systems, distributor for Prous Institute for Biomedical Research in Japan, has been invited to speak at the BIOtech 2015, part of Asia’s largest Bio event, Life Science World. On May 14, 2015 (Thu) 12:20-13:20, Atsushi Kanou, General Manager, Computational Science Dept., will present “Prous Institute Symmetry: Computational approach in drug discovery”, ...


Barcelona, Spain: The Prous Institute for Biomedical Research (PIBR) today announced a collaboration with the National Institute of Health’s National Center for Advancing Translational Sciences (NCATS) to help advance assessing environmental chemical and drug safety. The research goal is to develop and validate quantitative structure – activity relationship (QSAR) models as tools to pr...


Symmetry's Global Mechanism of Action (GMoA) model provides decision support in the multi-target approach to deliberately combine in a single molecule scaffolds related to different therapeutic targets. This case study is performed with molecules reported in a recent paper describing the first compound exhibiting gamma-Secretase modulation, PPARgamma agonism and 5-LOX inhibition for the potential ...


Prous Insitute is pleased to announce the launch of our new website showcasing the features and benefits of Symmetry, the world’s first integrated predictive platform for drug discovery and safety evaluation.  To visit the website please click here.   


Symmetry's Global Mechanism of Action (GMoA) model helps anticipate potential off-target safety liabilities of new structures early in drug discovery. This case study is performed with molecules reported in a recent paper describing the optimization of compounds for the potential treatment of Alzheimer ’s disease, minimizing cardiovascular liabilities (hERG channel blockade). To recei...

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