News & Publications

NEWS & PUBLICATIONS

Learn more about Prous Institute and our progress in drug discovery, technology, industry partnerships, collaborations and scientific articles.


A new paper co-authored by scientists at US FDA and Prous Institute for Biomedical Research describes the development and validation of a QSAR model to predict Salmonella t. mutagenicity (Ames assay outcome) of pharmaceutical impurities using Prous Institute SYMMETRY SM, the world’s first integrated in silico solution for drug discovery and safety screening.  Data was sourced from publi...


Prous Institute will participate in the Annual Genotoxic Impurities Conference to be held in Berlin, June 19-20th to present its new in silico predictive platform, SYMMETRY®.  Attendees will have the opportunity to learn about SYMMETRY®’s QSAR models for predicting the mutagenic potential of drug impurities in accordance with ICH M7, developed in collaboration with the U.S. FDA....


A new paper published by US FDA scientists (In silico modeling to predict drug-induced phospholipidosis; Sydney S. Choi, Jae S. Kim, Luis G. Valerio Jr., Nakissa Sadrieh;  Toxicol Appl Pharmacol. 269 (2013) 195–204) explores the use of Prous Institute’s SYMMETRY® in the construction and validation of QSAR models for the identification of drug-induced phospholipidosis (DIPL). T...


Berlin, Germany: Prous Institute for Biomedical Research has announced the presentation of study results using its proprietary computational platform, Symmetry®, to identify molecular and cellular targets involved in neuroplasticity and tumor cell proliferation at the 22nd International Symposium on Medicinal Chemistry organized by the European Federation of Medicinal Chemistry (EFMC). Prous...


Vienna, Austria: Prous Institute for Biomedical Research and the FDA Center for Drug Evaluation and Research (CDER) will present the results of their work to develop reliable mutagenicity models with a new release of Prous Institute’s Symmetry® computational platform and FDA/NCTR Mold2 descriptor package.  Prous Institute and the FDA/CDER are jointly presenting the research findings...

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