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Learn more about Prous Institute and our progress in drug discovery, technology, industry partnerships, collaborations and scientific articles.

Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans

2010 Nov 06 |

Part C: use of QSAR and an expert system for the estimation of the mechanism of action of drug-induced hepatobiliary and urinary tract toxicities. 

Describes the regulatory use of BioEpisteme and other predictive systems.

Authors: Matthews EJ, Kruhlak NL, Benz RD, Aragonés Sabaté D, Marchant CA, Contrera JF.

Journal: Regul Toxicol Pharmacol. 2009 Jun;54(1):43-65, PMID: 19422100

Link to Article

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