Part C: use of QSAR and an expert system for the estimation of the mechanism of action of drug-induced hepatobiliary and urinary tract toxicities.
Describes the regulatory use of BioEpisteme and other predictive systems.
Authors: Matthews EJ, Kruhlak NL, Benz RD, Aragonés Sabaté D, Marchant CA, Contrera JF.
Journal: Regul Toxicol Pharmacol. 2009 Jun;54(1):43-65, PMID: 19422100
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