A vast library of drug-like compounds (PSMEL
®) is being generated in silico at Prous Institute through a multistep process (IGSME
®) to fulill the needs of the
Epistemic Drug Discovery® project on autophagy and apoptosis modulation and type 2 diabetes.
The large chemical space created by PSMEL is orbited by
i-DDS, allowing the selection of compounds to be assessed for biological activity. In this space, it is possible to make
serendipitous discoveries.